49ers Injury Updates 2025: Purdy, Kittle Return & More | NFL Season Insights (2025)

Imagine a team’s season hanging in the balance, with key players sidelined by injuries—it’s a scenario that tests the depth and resilience of any roster. And this is exactly where the San Francisco 49ers find themselves right now. Quarterback Brock Purdy and tight end George Kittle, two cornerstone players, are finally returning to practice after extended injury absences, coach Kyle Shanahan confirmed. But here’s where it gets tricky: their availability for Sunday’s primetime clash against the Atlanta Falcons remains a mystery. Is this the turning point the 49ers need, or will their comeback be delayed?

Purdy, who hasn’t practiced since re-aggravating a toe injury in Week 4 against the Jacksonville Jaguars, has only played in two games this season. Backup quarterback Mac Jones has admirably stepped in, leading the team to a 3-1 record despite nursing his own oblique and left knee injuries. Shanahan noted, ‘Brock’s more limited than Mac,’ hinting that Jones might still be the safer bet for Sunday. But will Purdy’s return spark a much-needed offensive surge, or is it too soon to risk it?

Kittle, meanwhile, has been on injured reserve since a hamstring injury in the season opener against the Seattle Seahawks. Shanahan expressed hope earlier this week that Kittle could suit up against the Falcons, but his status remains uncertain. If he plays, could his presence on the field be the game-changer the 49ers desperately need?

Adding to the injury woes, wide receiver Ricky Pearsall is still out with a knee injury, and Jauan Jennings remains limited with ankle and rib issues. Pearsall had been a standout performer, leading the team with 327 receiving yards before his injury, while Jennings has battled through multiple injuries, including five broken ribs, missing two games this season. How will the 49ers offense adapt without their top receivers at full strength?

On the defensive side, linebacker Fred Warner underwent successful surgery to repair a dislocated and broken ankle, though Shanahan offered no timeline for his return. ‘We’re not thinking about that right now,’ he said, emphasizing the team’s focus on immediate challenges. Will Warner’s absence continue to leave a gaping hole in the defense?

As the 49ers navigate this injury-plagued season, one thing is clear: their depth is being tested like never before. But here’s the real question: Can they overcome these setbacks and make a playoff push, or will injuries derail their season? What do you think? Is this the week the 49ers turn their luck around, or are they in for another uphill battle? Let us know in the comments!

49ers Injury Updates 2025: Purdy, Kittle Return & More | NFL Season Insights (2025)

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